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br Materials and methods br Results br Discussion Energy
2020-08-04
Materials and methods Results Discussion Energy balance is monitored by the hypothalamus, where inhibitors of FAS have been described to suppress food intake [40], [41]. C75 acts on fatty-acid metabolism by inhibiting FAS activity. Inhibition of FAS produces accumulation of malonyl-CoA, whi
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The n alkanols are a well studied family
2020-08-04
The n-alkanols are a well-studied family with CPA. Various studies have been reported on their mixtures with other alkanols [15], [16], water [17], [18], amines [19] and hydrocarbons [16], [17], [18], [20], [21], [22], [23], as well as on other relevant properties of the pure compounds such as surf
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In various thermal recovery processes of heavy
2020-08-04
In various thermal recovery processes of heavy buy norethisterone and bitumens, e.g., Steam Assisted Gravity Drainage (SAGD) and Cyclic Steam Stimulation (CSS), hydrocarbons are produced by heating reservoir formations with a hot heat-carrying fluid such as water. Increasing temperature reduces the
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In summary here we found TGIF to function as
2020-08-04
In summary, here we found TGIF1 to function as a repressor of NPC1L1 and overexpression of TGIF1 in the intestine of mice to lower markers of intestinal cholesterol histone demethylase inhibitor and intestinal expression levels of Npc1l1, Abca1, Abcg5, and Abcg8. TGIF1 is thus a new player in intes
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Findings from previous register based studies
2020-08-04
Findings from previous register based studies favor ours as use of calcitriol hormone alone or in combination with progestogen among≥75year old women was not beneficial for cognitive performance [28]. Medical records based use of oral or parenteral estrogen use for ≥6 months among 264 AD cases and
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The genetic asymmetries between parental genomes are
2020-08-04
The genetic asymmetries between parental genomes are also the subject of genetic conflict theory. This concept proposes that paternally inherited imprinted genes “extract” nutrients from the mother during gestation. By contrast, maternally inherited genes counteract the effect of paternal genes (Con
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br Conclusion The past few years have witnessed substantial
2020-08-04
Conclusion The past few years have witnessed substantial progress in understanding the structural mechanisms of substrate recognition and the reactions catalyzed by the O-GlcNAc-cycling enzymes, but more work remains. In particular, future research will be needed to establish how OGT and OGA inte
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Omar Farha and coworkers have
2020-08-04
Omar Farha and coworkers have recently successfully employed metal-organic frameworks (MOFs) to tackle these limitations while retaining the essential characteristics of an immobilization material. MOFs consist of metal ions, or small clusters thereof, coordinated with organic ligands. MOFs are high
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br Acknowledgements br Introduction Botulinum neurotoxin
2020-08-04
Acknowledgements Introduction Botulinum neurotoxin (BoNT) is a uniquely potent protein synthesized by Clostridium botulinum, C. baratii and C. butyricum, (Rosetto et al., 2014, Kukreja and Singh, 2014). It acts on cholinergic nerve endings and blocks the release of Tn5 DNA Library for 5 ng DNA
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br Use of recombinant collagen to
2020-08-04
Use of recombinant collagen to study DDR–collagen interactions Synthetic peptides have proven highly valuable in replicating the characteristics of collagen and in defining the sites on collagen essential for binding and studying protein–collagen interactions. There are, however, disadvantages to
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In addition gestational GC induced adverse
2020-08-04
In addition, gestational GC-induced adverse birth outcome in the present study is in consonance with previous findings in experimental animals (Schwitzgebel et al., 2009). Adverse prenatal environment such as exposure to excess GC have been reported to lead to metabolic imprinting including intraute
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Drug induced toxicity is caused either by parent compounds o
2020-08-03
Drug-induced toxicity is caused either by parent compounds or by their reactive metabolites that are generated through biotransformation primarily in the liver (Srivastava et al., 2010). The cytochrome P450 (CYP) superfamily members contribute to approximately 80% of this process (Evans and Relling,
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Vitamin D3 Current studies in the BLA circuitry
2020-08-03
Current studies in the BLA circuitry underlying specific fear behaviors provide a framework for an improved understanding of the neurobiological underpinnings of alcohol use disorders and dependence. Notably, work on the specific alterations in amygdala microcircuitry produced by fear conditioning c
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Here we map the SYNE
2020-08-03
Here, we map the SYNE1 gene, a large gene with a complex transcriptional profile, which has been implicated in a variety of diseases. The first group includes muscular dystrophies; Emery–Dreifuss type muscular dystrophy and autosomal recessive arthrogryposis, which are conditions that severely affec
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Yang et al studied anti
2020-08-03
Yang et al. studied anti-inflammatory and antioxidant activities of methanol extract of the fruits of Foeniculum vulgare (F. vulgare) traditionally used to treat inflammatory diseases. Four coumarins viz scopoletin 13, 8-methoxypsoralen 14, bergapten 15 and imperatorin 16 were isolated. Although fou
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