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cetrizine Second due in large part to data limitations few s
2018-10-24
Second, due in large part to data limitations, few studies have investigated ancestral health disparities among second-generation black immigrants, which conceals the increasing heterogeneity of the second-generation black immigrant population. Immigrants from the Caribbean have historically compris
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br Methods br Results br Discussion This
2018-10-24
Methods Results Discussion This study investigated which drug categories were responsible for the growth in fatal overdoses between 1999 and 2014 or sub-periods. Three challenges were encountered when attempting to answer this seemingly simple question. First, current death certificate data
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Estimados Lectores En sus manos tienen el n mero de
2018-10-23
Estimados Lectores: En sus manos tienen el número 400 de Economía Informa, lo cual representa un motivo de orgullo y festejo para nuestra comunidad; especialmente para quienes han hecho posible su existencia y su publicación periódica durante todos estos años; me refiero no solo meanwhile los profe
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present here a fundamental insight into
2018-10-23
present here a fundamental insight into the nature of primary varicose vein disease. They attempt to determine if the methylenetetrahydrofolate reductase polymorphisms (MTHFR C677T and A1298C) are implied in the morphology and types of complicated disease in patients with primary varicose veins. The
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br NGS Panel for Diagnosis of
2018-10-23
NGS Panel for Diagnosis of Early and Severe Forms of Polycystic Kidney Disease Polycystic kidney disease (PKD) is one of the most common potentially life-threatening human genetic disorders, and early and severe PKD occur in patients with the autosomal recessive form (ARPKD) and 2–5% of the autos
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We devised a type of intervention that
2018-10-23
We devised a type of intervention that, if successful, could be further tested in larger trials and, ultimately, translated into general practice. We focused on pregnant women known to be at increased risk of infection, i.e., women caring for young children. These women were first offered CMV testin
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br Limitations Though the use
2018-10-23
Limitations Though the use of organ- or tissue-on-a-chip devices shows a great deal of promise for future applications, it is important to remember that these are relatively new technologies and require further advancements prior to widespread use. It is first necessary to characterize these devi
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When untargeted analysis is considered pharmacometabolomics
2018-10-23
When untargeted analysis is considered, pharmacometabolomics also serves as a tool to shape hypothesis, as multiple analytes are quantified simultaneously and pharmacometabolomic modeling appears not to be limited by prior understanding or hypotheses. Hence, pharmacometabolomic modeling can be a pow
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One of the pivotal drugs in the
2018-10-23
One of the pivotal drugs in the regimen used to treat children with both drug-susceptible and MDR-TB, based on equivalent use in adults, is pyrazinamide (Donald et al., 2012). The doses for use in children are as yet unclear; based on computer aided clinical trial simulations we and others have prop
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The additive impact of progressive changes
2018-10-23
The additive impact of progressive changes in sleep quality and structure, changes in cerebral blood flow, neurovascular and neurotransmitters, plus the cellular redox status are all likely to contribute to the cognitive deficits reported in up to one out of four newly diagnosed OSA patients (Rosenz
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The second part of this study evaluated the detection
2018-10-23
The second part of this study evaluated the detection of NTM in clinical specimens by PCR in comparison to culture (Fig. 2). Here we used the Roche COBAS™ MTB assay supplemented with an additional pan Mycobacterium genus probe. The Mycobacterium genus probe is highly sensitive but compromised by lim
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br Methods We searched PubMed and Medline
2018-10-23
Methods We searched PubMed and Medline for papers on revaccination with BCG, MV, OPV and smallpox vaccine and mortality/death. The literature searches are explained in Supplementary Figs. 1–4. WHO recently organised a major review of the potential nonspecific effects of BCG histone acetyltransfer
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In a single study using a murine knockout model significant
2018-10-23
In a single study using a murine knockout model, significant reductions both in litter size and fetal weight in ANXA5-null mice (ANXA5-KO) was reported (Ueki et al., 2012), if accepted this suggests that maternal expression of ANXA5 in the circulation may be crucial for maintaining normal pregnancy;
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Our previous study demonstrated that
2018-10-23
Our previous study demonstrated that HDAC inhibition contributed to the anticancer effect of statins (Lin et al., 2008). Combining anti-cancer drugs with different mechanisms is a rational approach to improve efficacy. JMF3086, synthesized to inhibit both HDACs and HMGR, exhibits significant benefit
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NO is implicated in various other
2018-10-23
NO is implicated in various other pathological conditions in the brain, including excitotoxicity during ischemic BMS-754807 injury (Nakamura et al., 2013; Pacher et al., 2007). For instance, in the middle cerebral artery occlusion model, the brain injury is milder in mice treated with an nNOS-speci
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