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We found that the STX R Q variant has
2018-11-15

We found that the STX1 R/Q variant has decreased phosphorylation of Ser14, a key residue involved in the functional regulation of STX1 (Khelashvili et al., 2012; Dubois et al., 2002). STX1 in this hypo-phosphorylated state fails to support DAT-mediated reverse transport of DA without inhibiting DA u
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br Conflict of interest br Acknowledgements
2018-11-15

Conflict of interest Acknowledgements This work was supported by a grant from the Belgian National Fund for Scientific Research (FNRS 3.4.516.08.F). Stéphane A. De Brito was supported by a research fellowship from the Swiss National Science Foundation (SNSF PA00P1_139586). Introduction Att
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Adolescents in this study averaged over h
2018-11-15

Adolescents in this study averaged over 8h of sleep per night, which is similar to what has been obtained in other studies with this age group (Wolfson and Carskadon, 1998; Fuligni and Hardway, 2006) and is close to the number of hours recommended for adolescents (Wolfson and Carskadon, 1998). Yet,
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Replicating prior studies we found that
2018-11-15

Replicating prior studies, we found that non-anxious individuals are capable of learning from positive outcomes, regardless of age (Moutsiana et al., 2013). However, this ability was impaired in both anxious adolescents and adults. Although anxious adolescents recalled expected Etonogestrel from hi
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As first described by Spence the transverse
2018-11-15

As first described by Spence (1952), the transverse patterning problem comprises 3 concurrent discriminations with overlapping stimuli (see Fig. 1). The three problems take the following form: Problem 1 A+ vs. B− (where+and − indicate the correct and incorrect choices respectively), Problem 2 B+ vs.
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The fact that hub regions constitute
2018-11-15

The fact that hub regions constitute potential points of vulnerability for network disintegration is a key issue (Albert et al., 2000). Indeed, the abnormalities associated with several T-5224 disorders have been shown to concentrate in hubs; such disorders include ADHD (dos Santos Siqueira et al.,
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The tensile properties of the
2018-11-15

The tensile properties of the two alloys at a wide range of strain rates have been investigated [16]. The tensile tests of the two alloys at low strain rate were performed on a standard tensile test machine. A split-Hopkinson tension bar (SHPT) was used for the tensile test at high strain rate. The
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br Diagnosis br Discussion Adult T cell lymphoma leukemia
2018-11-15

Diagnosis Discussion Adult T cell lymphoma/leukemia (ATLL) is a malignant lymphoproliferative disease caused by HTLV-I. HTLV-I infection is endemic in southern Japan, the Caribbean Islands, South America, and possibly some areas of northern Taiwan. More than 90% of infected persons are asympto
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Haptens are chemicals that are chemically reactive and have
2018-11-15

Haptens are chemicals that are chemically reactive and have a tendency to build covalent bonds to some AAs within a protein. For example, at least 13 lysine groups within the albumin molecule have been shown to bind piperacillin and were processed to different modified epitopes within the same prote
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br Acknowledgments br Introduction Psoriatic skin lesions ar
2018-11-15

Acknowledgments Introduction Psoriatic skin lesions are characterized by histological evidence of inflammation, abnormal keratinocyte proliferation/terminal differentiation, and dermal angiogenesis. Although the etiology of psoriasis remains unknown, it is clear that an interaction among genet
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Our research shows that many of these problems can
2018-11-15

Our research shows that many of these problems can be solved by using many-particle interaction [20–22]. Note that the construction of such relations becomes possible due to using a hybrid computational technique to combine the mathematical formalisms of discrete elements and cellular automata [23].
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The mean stress in the automaton
2018-11-15

The mean stress in the automaton volume at the pressure P can be determined from the calculated stress tensor components Tensor components allow us to calculate the other tensor invariants in the automaton volume, in particular stress intensity From Eqs. (1)–(3) it follows that the specific form o
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A review on the literature backgrounds of
2018-11-14

A review on the literature backgrounds of the designs of Palladio and Sinan yields two observations. First, the architectural library is rich with research and publications on the works of Palladio and Sinan, each studied independently. Examples include the studies on Palladio׳s designs (Ackerman, 1
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br Methods br Results br
2018-11-14

Methods Results Discussion Is it possible to predict the social structure of space using space syntax techniques? The answer appears to be positive. The first proposal, with the straight linear pathway, did not show significant changes in the visual integration analysis through Depthmap. Th
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One month after the excisional biopsy
2018-11-14

One month after the excisional biopsy of the back nodule, the patient developed high fever with cough. At that time, a physical examination showed yellowish skin discoloration, coarse breathing sounds over both lung fields, and negative findings for the abdomen. The routine workup included sputum cu
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