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br Methods We searched PubMed and Medline
2018-10-23
Methods We searched PubMed and Medline for papers on revaccination with BCG, MV, OPV and smallpox vaccine and mortality/death. The literature searches are explained in Supplementary Figs. 1–4. WHO recently organised a major review of the potential nonspecific effects of BCG histone acetyltransfer
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In a single study using a murine knockout model significant
2018-10-23
In a single study using a murine knockout model, significant reductions both in litter size and fetal weight in ANXA5-null mice (ANXA5-KO) was reported (Ueki et al., 2012), if accepted this suggests that maternal expression of ANXA5 in the circulation may be crucial for maintaining normal pregnancy;
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Our previous study demonstrated that
2018-10-23
Our previous study demonstrated that HDAC inhibition contributed to the anticancer effect of statins (Lin et al., 2008). Combining anti-cancer drugs with different mechanisms is a rational approach to improve efficacy. JMF3086, synthesized to inhibit both HDACs and HMGR, exhibits significant benefit
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NO is implicated in various other
2018-10-23
NO is implicated in various other pathological conditions in the brain, including excitotoxicity during ischemic BMS-754807 injury (Nakamura et al., 2013; Pacher et al., 2007). For instance, in the middle cerebral artery occlusion model, the brain injury is milder in mice treated with an nNOS-speci
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The analysis of the correlation matrix revealed that the
2018-10-23
The analysis of the correlation matrix revealed that the different administration procedures presented positive and significant correlations between each other (Table 3). There was a significant association between performance on the TICSM-PT VC and the TICSM-PT telephone scores (r=0.885, pSM-PT ass
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Remarkably Cornelius et al report
2018-10-23
Remarkably, Cornelius et al. report for the first time HBV-neutralizing antibodies in all seven so-far tested human recipients of the BM32 vaccine, i.e., of preS antigen without other HBV antigens. Assay of neutralizing antibodies has been difficult because for long time the only HBV-susceptible cel
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It has previously been hypothesised that iron supplementatio
2018-10-23
It has previously been hypothesised that iron supplementation increases malaria susceptibility by increasing the availability of \'s preference for young RBCs (). observed significant shifts in RBC populations following iron supplementation, finding younger RBCs are most prevalent at Day 49 post iro
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SAMD appears to be a central mediator for interventions that
2018-10-23
SAMD appears to be a central mediator for interventions that extend healthy lifespan. Dietary restriction induces autophagy, improves mitochondrial function, specifically in complex I (Miwa et al., 2014) and reduces frequencies of senescent ubiquitin activating enzyme in many tissues (Wang et al., 2
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br Conclusions and Future Questions In this
2018-10-23
Conclusions and Future Questions In this review, we have summarized current knowledge on biological age predictors and discussed different data types used. There are several existing predictors, where the most plausible candidates are the epigenetic clock and telomere length. They have both been
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The objective was to understand the
2018-10-23
The objective was to understand the integrin inhibitor of this organism across Europe and to get insight into the geographical and temporal evolution of the different genotypes. The diversity of P. jirovecii isolates responsible for PCP across different European countries (n=12) was investigated, in
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br Data experimental design materials and methods
2018-10-23
Data, experimental design, materials and methods Boron (B)-tolerant ‘Xuegan’ (Citrus sinensis) and B-intolerant ‘Sour pummelo’ (Citrus grandis) seedlings were used to investigate the effects of B-toxicity on leaf proteomics. Plant culture and B treatments were performed as described previously [1
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br Data In order to inform the SPIDIA
2018-10-23
Data In order to inform the SPIDIA-DNA EQA participants on the quality of the extracted DNA from blood a dedicated report was realized [1,4]. The report contains the evaluation of the performance of the specific laboratory and the overall distribution of the participants’ data for each gDNA quali
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Workflow Mascot Distiller Mascot Skyline MS Signal analysis
2018-10-23
Workflow 8: Mascot Distiller/Mascot/Skyline/MS Signal analysis. Peaklist creation was performed with Mascot Distiller as described in workflow 3, then database searches were performed with Mascot and validated with Scaffold as described for workflow 4. XIC signal corresponding to all validated pepti
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br Introduction The electromagnetic railgun is
2018-10-22
Introduction The electromagnetic railgun is a kinetic smo inhibitor weapon utilizing an electromagnetic force produced by a high power pulse current to accelerate a projectile to a high speed. It has wide applications in military and civil fields [1–3]. How to extend the lifetime of the launcher
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La met fora del pan ptico es
2018-10-22
La metáfora del panóptico es fundamental en la obra de Eltit. En todas sus novelas existe esta tensión entre un ojo de poder que intenta aprehender hcv protease inhibitor ciertos personajes y que estos tratan de evitar, como sucede con la protagonista de Lumpérica con la luz del luminoso y la cámara
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