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rora br LEGADO FUJIMORISTA No seu
2019-05-21
LEGADO FUJIMORISTA No seu segundo mandato, García abandonou as veleidades esquerdistas realizando um governo abertamente neoliberal. Embora em campanha criticasse o modelo de exploração mineira em que se assentava o crescimento peruano, praticamente eximindo as empresas de obrigações tributárias
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The management of PEComa follows the same treatment
2019-05-21
The management of PEComa follows the same treatment principles as other subtypes of soft tissue sarcoma. Surgical resection remains the primary treatment modality. There is no consensus on the administration of adjuvant treatment. Other treatment options, including chemotherapy and radiotherapy, hav
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Contributors Conflicts of interest br Acknowledgments This r
2019-05-21
Contributors Conflicts of interest Acknowledgments This research was funded by the Bill & Melinda Gates Foundation. The views expressed herein are those leucine enkephalin of the authors and do not necessarily represent the official policy or position of the Bill & Melinda Gates Foundation, Imp
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Numerous clinical trials phase II and phase III
2019-05-20
Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M
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Both breast cancer and MM cause osteolytic lesions inhibitin
2019-05-20
Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit
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br Discussion and outstanding questions Reproductive endocri
2019-05-20
Discussion and outstanding questions Reproductive endocrine hormones such as inhibin affect breast cancer cell survival in the primary tumour and affect tumour homing and survival in the bone microenvironment. The molecular mechanism driving this effect of hormones in bone is likely to be multifa
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br Results There were cases where cryotherapy was
2019-05-20
Results There were 232 cases where cryotherapy was used in 214 patients between 1994 and 2015. There were 96 male and 118 female. The age of patients ranged from 4 to 95. All patients had undergone imaging studies for evaluation. A majority of cases consisted of active or aggressive benign tumors
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In silico prediction software SIFT PolyPhen CADD and other p
2019-05-20
In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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A type saddle back type or type ST segment elevation
2019-05-20
A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b
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Rat Erythropoietin / EPO Protein (His Tag) El n mero de cor
2019-05-20
El número 61 de , correspondiente al segundo semestre de 2015, ofrece seis artículos en su sección Política y Sociedad. El primero Rat Erythropoietin / EPO Protein (His Tag) cargo de Wilfredo Padrón Iglesias, “La masonería, un punto sombrío en la trayectoria de Francisco de Miranda”, trata sobre es
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br Eva Leticia Ordu a Trujillo investigadora del en
2019-05-20
Eva Leticia Orduña Trujillo, investigadora del en uno de sus más recientes libros , aborda un tema fundamental para explorar, debatir y profundizar sobre nuestras aún muy débiles democracias latinoamericanas, BMN673 través de la actuación de nuestros estados en sedes judiciales internacionales. ¿Y
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Avasimibe In the days before Christmas
2019-05-20
In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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Findings Final data analysis included households nine from t
2019-05-20
Findings Final data analysis included 28 households: nine from the Tulip filter group, 10 from Waterguard chlorination, and nine from the group who boiled water. Two households had incomplete data and were excluded from analysis. Before the intervention, 29 of 30 households were not treating their w
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The BrS ECG is often widely dynamic with ST segment
2019-05-20
The BrS ECG is often widely dynamic, with ST segment elevations that fluctuate from hour to hour, day to day, and month to month. Diurnal variation shows that events occur more frequently at night during periods of high vagal tone [2]. In some patients, the use of frequent ECGs or 12-lead ambulatory
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Express o territorial desta expans o no in
2019-05-20
Expressão territorial desta expansão, no início dos anos 1990 as concessões mineiras ocupavam 2.3 milhões de hectares, enquanto na atualidade, beiram 25 milhões. A atividade deixou de se concentrar nas alturas andinas expandindo‐se para os vales, kras-pdeδ pathway costa e inclusive a Amazônia. Há de
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